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Antibody Engineering

Name: Antibody Engineering
Brand: Humana Press Inc.
SKU: 01430225
Price: 154.55 EUR
Availability: InStock
Author: Benny K. C. Lo
ISBN: 9781588290922

Methods and Protocols

Benny K. C. Lo

Language

English

Book Hardback

Libristo code: 01430225

Publishers Humana Press Inc., December 2003

A core collection of diverse cutting-edge techniques for the generation, expression, optimization, a... Full description

Libristo code: 01430225

373 b

154.55 €

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A core collection of diverse cutting-edge techniques for the generation, expression, optimization, and characterization of recombinant antibodies. Readily reproducible protocols for lead generation range from the cloning of human immunoglobulin genes to the selection and generation of human recombinant antibodies by humanization approaches, molecular display technologies and transgenic animals. Procedures are also described on restructuring antibody leads into monovalent, multivalent, and bispecific binding fragments for a wide variety of in vivo applications. State-of-the-art technologies are described for the characterization of antigen-binding affinity and specificity with novel applications in radioimmunotargeting, cancer immunotherapy, drug abuse, and proteomics.