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Biological Sequence Analysis

Theory, Algorithms, and Applications

Language EnglishEnglish
Book Paperback
Book Biological Sequence Analysis Fangrui Ma
Libristo code: 12627042
Publishers Scholars' Press, February 2013
With more and more biological sequences available, sequence analyses have become very important in... Full description
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With more and more biological sequences available, sequence analyses have become very important in bioinformatics and computational biology. In this book, we present the results of our research on genome sequence alignment, RNA folding with simple pseudoknots, and single nucleotide polymorphism (SNP) association pattern discovery with spatial constraints. In genome sequence alignment, we use the divide and conquer approach to reduce the computational complexity of multiple whole genome sequence alignment. Furthermore, we introduced the concept of solution space of genome sequence alignment to solve the problem that the current genome sequence alignment algorithms do not consider spatial constraints. The solution space is modeled as a multi-bipartite digraph. We provide efficient graph decomposition and traversal algorithms for processing the graph to output solutions as alignments of functionally equivalent clusters.

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About the book

Full name Biological Sequence Analysis
Language English
Binding Book - Paperback
Date of issue 2013
Number of pages 184
EAN 9783639512182
ISBN 3639512189
Libristo code 12627042
Publishers Scholars' Press
Weight 277
Dimensions 152 x 229 x 11
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