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Gene Prioritization

Name: Gene Prioritization
Brand: Springer, Berlin
SKU: 02432595
Price: 57.24 EUR
Availability: InStock
Author: Ali Masoudi-Nejad
ISBN: 9783319046860

Rationale, Methodologies and Algorithms

Ali Masoudi-Nejad

Alireza Meshkin

Language

English

Book Paperback

Libristo code: 02432595

Publishers Springer, Berlin, March 2014

Identifying causal genes underlying susceptibility to human disease is a problem of primary importan... Full description

Libristo code: 02432595

139 b

57.24 €

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Identifying causal genes underlying susceptibility to human disease is a problem of primary importance in the post-genomic era and in current biomedical research. Recently, there has been a paradigm shift of such gene-discovery efforts from rare, monogenic conditions to common oligogenic or multifactorial conditions such as asthma, diabetes, cancers and neurological disorders. These conditions are referred to as multifactorial because, susceptibility to these diseases is attributed to the combinatorial effects of genetic variation at a number of different genes and their interaction with relevant environmental exposures. The goal of this book is to introduce gene prioritization aspects and the candidate gene prioritization algorithms to give readers a comprehensive view on the subject.