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Perspectives on Biologically Based Cancer Risk Assessment

Name: Perspectives on Biologically Based Cancer Risk Assessment
Brand: Springer Science+Business Media
SKU: 01379073
Price: 153.15 EUR
Availability: InStock
Author: Vincent James Cogliano
ISBN: 9780306461088

Vincent James Cogliano

E. Georg Luebeck

Giovanni A. Zapponi

Language

English

Book Hardback

Libristo code: 01379073

Publishers Springer Science+Business Media, July 1999

The book includes a comprehensive updated analysis of cancer risk assessment procedures, with partic... Full description

Libristo code: 01379073

373 b

153.15 €

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The book includes a comprehensive updated analysis of cancer risk assessment procedures, with particular attention to biologically-based modelling. The presented arguments include the basic assumptions of cancer risk assessment methods, their biological basis and theoretical background, the relevant data sources, the multistage models (including the two-stage and clonal expansion models and pharmacokinetic models), and the relevant biomarkers, together with fundamental statistical considerations and selected case studies and examples of practical applications. The uncertainty of assessment and the practical use of the proposed methods are also discussed and possible new developments suggested. The book examines in detail the updated biologically-based carcinogenic risk assessment procedures together with the usually employed procedures, as well as background information on which they are based. It also proposes new ideas and methods in this field. Furthermore, it includes criteria and methods for practical application and use of the examined procedures.