End of Alzheimer's

The entire research and treatment approach for Alzheimer’s sufferers at present is focused on the brain only, with much of the research, drug development, and emerging treatments focused on the two presumed hallmarks in the brain, amyloid plaques and neurofibrillary tangles. However, there are many examples of Alzheimer’s outside the brain including the heart, the eyes, and muscles along with its connection to diabetes. The molecular research into these concepts is captured in some research articles but not in any comprehensive book on Alzheimer’s until now. The End of Alzheimer’s: The Brain and Beyond is the first comprehensive overview on the molecular basis of Alzheimer’s outside of the brain, merging the most recent findings within this field into a single book. It aims to educate the reader on the many aspects of Alzheimer’s disease that occur outside the brain but are overlooked. This book uniquely provides step-by-step peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer’s outside the brain, and argues that a more thorough, whole-body diagnosis will provide better answers about the causes and lead to new treatments. This book is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer’s, and will hopefully redirect many into new avenues of cellular research and discovery. Comprehensive literature-based summary of the current state of molecular Alzheimer’s disease researchDetails the shortcomings of the prevailing model and therapeutics in developmentReviews blood-based biomarkers for Alzheimer’s and their link to amyloid- and Tau-independent causes outside the brainDescribes the tissues outside the brain impacted by Alzheimer’s and the underlying molecular causesExplains the whole-body risks associated with Alzheimer’s and concomitant measures to slow or prevent the diseaseProvides a protocol to properly research, evaluate, measure, diagnose, and potentially treat Alzheimer’s patients