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Inflammatory Processes
: Molecular Mechanisms and Therapeutic Opportunities
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In November 1998 many of the key leaders of new drug discovery for
inflammatory diseases gathered at Hershey, Pennsylvania for the 9th
International Conference of the Inflammation Research Association. The
Conference was held over a five day period and provided a stimulating
environment for the open exchange of important advances in basic
inflammation research as well as new drug discovery and development.
This book encompasses some of the highlights of several presentations
made at the Conference. It contains some of the latest and important
developments in the field of inflammation research.
Topics include the status of eotaxin and chemokines in asthma and
allergy, signal transduction and regulation of diverse mediators such as
the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as
regulators of AP-1, macrophage metalloproteinases, lymphotoxin and
further insights into the role of MCP-1 in disease. Also discussed are
drug targets in rheumatoid and osteoarthritis, fibrotic diseases,...
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